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Regulation of nucleotide excision repair activity by transcriptional and post-transcriptional control of the XPA protein

The XPA (Xeroderma pigmentosum A) protein is one of the six core factors of the human nucleotide excision repair system. In this study we show that XPA is a rate-limiting factor in all human cell lines tested, including a normal human fibroblast cell line. The level of XPA is controlled at the trans...

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Detalles Bibliográficos
Autores principales: Kang, Tae-Hong, Reardon, Joyce T., Sancar, Aziz
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082913/
https://www.ncbi.nlm.nih.gov/pubmed/21193487
http://dx.doi.org/10.1093/nar/gkq1318