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Structures and activities of archaeal members of the LigD 3′-phosphoesterase DNA repair enzyme superfamily
LigD 3′-phosphoesterase (PE) is a component of the bacterial NHEJ apparatus that performs 3′-end-healing reactions at DNA breaks. The tertiary structure, active site and substrate specificity of bacterial PE are unique vis–à-vis other end-healing enzymes. PE homologs are present in archaea, but thei...
Autores principales: | Smith, Paul, Nair, Pravin A., Das, Ushati, Zhu, Hui, Shuman, Stewart |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082917/ https://www.ncbi.nlm.nih.gov/pubmed/21208981 http://dx.doi.org/10.1093/nar/gkq1163 |
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