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Amyloid Precursor Protein Is Trafficked and Secreted via Synaptic Vesicles

A large body of evidence has implicated amyloid precursor protein (APP) and its proteolytic derivatives as key players in the physiological context of neuronal synaptogenesis and synapse maintenance, as well as in the pathology of Alzheimer's Disease (AD). Although APP processing and release ar...

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Detalles Bibliográficos
Autores principales: Groemer, Teja W., Thiel, Cora S., Holt, Matthew, Riedel, Dietmar, Hua, Yunfeng, Hüve, Jana, Wilhelm, Benjamin G., Klingauf, Jürgen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083403/
https://www.ncbi.nlm.nih.gov/pubmed/21556148
http://dx.doi.org/10.1371/journal.pone.0018754