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Developmental Enhancement of Adenylate Kinase-AMPK Metabolic Signaling Axis Supports Stem Cell Cardiac Differentiation
BACKGROUND: Energetic and metabolic circuits that orchestrate cell differentiation are largely unknown. Adenylate kinase (AK) and associated AMP-activated protein kinase (AMPK) constitute a major metabolic signaling axis, yet the role of this system in guiding differentiation and lineage specificati...
Autores principales: | Dzeja, Petras P., Chung, Susan, Faustino, Randolph S., Behfar, Atta, Terzic, Andre |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083437/ https://www.ncbi.nlm.nih.gov/pubmed/21556322 http://dx.doi.org/10.1371/journal.pone.0019300 |
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