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Neuromuscular synaptic patterning requires the function of skeletal muscle dihydropyridine receptors

Developing skeletal myofibers in vertebrates are intrinsically “pre-patterned” for motor nerve innervation. However, the intrinsic factors that regulate muscle pre-patterning remain unknown. Here we show that a functional skeletal muscle dihydropyridine receptor (DHPR, the L-type Ca(2+) channel in m...

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Detalles Bibliográficos
Autores principales: Chen, Fujun, Liu, Yun, Sugiura, Yoshie, Allen, Paul D., Gregg, Ronald G., Lin, Weichun
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083454/
https://www.ncbi.nlm.nih.gov/pubmed/21441923
http://dx.doi.org/10.1038/nn.2792