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Deletion of a remote enhancer near ATOH7 disrupts retinal neurogenesis, causing NCRNA disease
Individuals with nonsyndromic congenital retinal nonattachment (NCRNA) are totally blind from birth. The disease afflicts ~1% of Kurdish people living in a group of neighboring villages in North Khorasan, Iran. We show NCRNA is caused by a 6523bp deletion that spans a remote cis regulatory element 2...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083485/ https://www.ncbi.nlm.nih.gov/pubmed/21441919 http://dx.doi.org/10.1038/nn.2798 |