Hemophagocytic syndrome secondary to cytomegalovirus infection in an infant

Virus associated hemophagocytic syndrome is a non-neoplastic, generalized histiocytic proliferation with prominent hemophagocytosis associated with a systemic viral infection. We report a case of cytomegalovirus (CMV) associated hemophagocytic syndrome in a 2 month old male child presenting with ras...

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Autores principales: Gupta, Anshu, Sen, Rajiv, Batra, Charu, Banerjee, Dipankar, Gupta, Anjali, Jain, Medha
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications Pvt Ltd 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083534/
https://www.ncbi.nlm.nih.gov/pubmed/21552407
http://dx.doi.org/10.4103/0970-9371.76949
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author Gupta, Anshu
Sen, Rajiv
Batra, Charu
Banerjee, Dipankar
Gupta, Anjali
Jain, Medha
author_facet Gupta, Anshu
Sen, Rajiv
Batra, Charu
Banerjee, Dipankar
Gupta, Anjali
Jain, Medha
author_sort Gupta, Anshu
collection PubMed
description Virus associated hemophagocytic syndrome is a non-neoplastic, generalized histiocytic proliferation with prominent hemophagocytosis associated with a systemic viral infection. We report a case of cytomegalovirus (CMV) associated hemophagocytic syndrome in a 2 month old male child presenting with rashes, fever, hepatosplenomegaly, cervical lymphadenopathy and pancytopenia. Fine needle aspiration cytology and biopsy from cervical lymph nodes revealed prominent hemophagocytosis. Serology for CMV IgM was positive in both the mother and the child, suggesting recent infection. Possibly there was intrauterine transmission of the infection.
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spelling pubmed-30835342011-05-06 Hemophagocytic syndrome secondary to cytomegalovirus infection in an infant Gupta, Anshu Sen, Rajiv Batra, Charu Banerjee, Dipankar Gupta, Anjali Jain, Medha J Cytol Case Report Virus associated hemophagocytic syndrome is a non-neoplastic, generalized histiocytic proliferation with prominent hemophagocytosis associated with a systemic viral infection. We report a case of cytomegalovirus (CMV) associated hemophagocytic syndrome in a 2 month old male child presenting with rashes, fever, hepatosplenomegaly, cervical lymphadenopathy and pancytopenia. Fine needle aspiration cytology and biopsy from cervical lymph nodes revealed prominent hemophagocytosis. Serology for CMV IgM was positive in both the mother and the child, suggesting recent infection. Possibly there was intrauterine transmission of the infection. Medknow Publications Pvt Ltd 2011 /pmc/articles/PMC3083534/ /pubmed/21552407 http://dx.doi.org/10.4103/0970-9371.76949 Text en Copyright: © Journal of Cytology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gupta, Anshu
Sen, Rajiv
Batra, Charu
Banerjee, Dipankar
Gupta, Anjali
Jain, Medha
Hemophagocytic syndrome secondary to cytomegalovirus infection in an infant
title Hemophagocytic syndrome secondary to cytomegalovirus infection in an infant
title_full Hemophagocytic syndrome secondary to cytomegalovirus infection in an infant
title_fullStr Hemophagocytic syndrome secondary to cytomegalovirus infection in an infant
title_full_unstemmed Hemophagocytic syndrome secondary to cytomegalovirus infection in an infant
title_short Hemophagocytic syndrome secondary to cytomegalovirus infection in an infant
title_sort hemophagocytic syndrome secondary to cytomegalovirus infection in an infant
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083534/
https://www.ncbi.nlm.nih.gov/pubmed/21552407
http://dx.doi.org/10.4103/0970-9371.76949
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AT banerjeedipankar hemophagocyticsyndromesecondarytocytomegalovirusinfectioninaninfant
AT guptaanjali hemophagocyticsyndromesecondarytocytomegalovirusinfectioninaninfant
AT jainmedha hemophagocyticsyndromesecondarytocytomegalovirusinfectioninaninfant

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