Cargando…
Mycosporine-Like Amino Acids: Relevant Secondary Metabolites. Chemical and Ecological Aspects
Taxonomically diverse marine, freshwater and terrestrial organisms have evolved the capacity to synthesize, accumulate and metabolize a variety of UV-absorbing substances called mycosporine-like amino acids (MAAs) as part of an overall strategy to diminish the direct and indirect damaging effects of...
Autores principales: | , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083659/ https://www.ncbi.nlm.nih.gov/pubmed/21556168 http://dx.doi.org/10.3390/md9030387 |
_version_ | 1782202433269661696 |
---|---|
author | Carreto, Jose I. Carignan, Mario O. |
author_facet | Carreto, Jose I. Carignan, Mario O. |
author_sort | Carreto, Jose I. |
collection | PubMed |
description | Taxonomically diverse marine, freshwater and terrestrial organisms have evolved the capacity to synthesize, accumulate and metabolize a variety of UV-absorbing substances called mycosporine-like amino acids (MAAs) as part of an overall strategy to diminish the direct and indirect damaging effects of environmental ultraviolet radiation (UVR). Whereas the enzymatic machinery to synthesize MAAs was probably inherited from cyanobacteria ancestors via the endosymbionts hypothesis, metazoans lack this biochemical pathway, but can acquire and metabolize these compounds by trophic transference, symbiotic or bacterial association. In this review we describe the structure and physicochemical properties of MAAs, including the recently discovered compounds and the modern methods used for their isolation and identification, updating previous reviews. On this basis, we review the metabolism and distribution of this unique class of metabolites among marine organism. |
format | Text |
id | pubmed-3083659 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Molecular Diversity Preservation International |
record_format | MEDLINE/PubMed |
spelling | pubmed-30836592011-05-09 Mycosporine-Like Amino Acids: Relevant Secondary Metabolites. Chemical and Ecological Aspects Carreto, Jose I. Carignan, Mario O. Mar Drugs Review Taxonomically diverse marine, freshwater and terrestrial organisms have evolved the capacity to synthesize, accumulate and metabolize a variety of UV-absorbing substances called mycosporine-like amino acids (MAAs) as part of an overall strategy to diminish the direct and indirect damaging effects of environmental ultraviolet radiation (UVR). Whereas the enzymatic machinery to synthesize MAAs was probably inherited from cyanobacteria ancestors via the endosymbionts hypothesis, metazoans lack this biochemical pathway, but can acquire and metabolize these compounds by trophic transference, symbiotic or bacterial association. In this review we describe the structure and physicochemical properties of MAAs, including the recently discovered compounds and the modern methods used for their isolation and identification, updating previous reviews. On this basis, we review the metabolism and distribution of this unique class of metabolites among marine organism. Molecular Diversity Preservation International 2011-03-21 /pmc/articles/PMC3083659/ /pubmed/21556168 http://dx.doi.org/10.3390/md9030387 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Review Carreto, Jose I. Carignan, Mario O. Mycosporine-Like Amino Acids: Relevant Secondary Metabolites. Chemical and Ecological Aspects |
title | Mycosporine-Like Amino Acids: Relevant Secondary Metabolites. Chemical and Ecological Aspects |
title_full | Mycosporine-Like Amino Acids: Relevant Secondary Metabolites. Chemical and Ecological Aspects |
title_fullStr | Mycosporine-Like Amino Acids: Relevant Secondary Metabolites. Chemical and Ecological Aspects |
title_full_unstemmed | Mycosporine-Like Amino Acids: Relevant Secondary Metabolites. Chemical and Ecological Aspects |
title_short | Mycosporine-Like Amino Acids: Relevant Secondary Metabolites. Chemical and Ecological Aspects |
title_sort | mycosporine-like amino acids: relevant secondary metabolites. chemical and ecological aspects |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083659/ https://www.ncbi.nlm.nih.gov/pubmed/21556168 http://dx.doi.org/10.3390/md9030387 |
work_keys_str_mv | AT carretojosei mycosporinelikeaminoacidsrelevantsecondarymetaboliteschemicalandecologicalaspects AT carignanmarioo mycosporinelikeaminoacidsrelevantsecondarymetaboliteschemicalandecologicalaspects |