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Mycosporine-Like Amino Acids: Relevant Secondary Metabolites. Chemical and Ecological Aspects

Taxonomically diverse marine, freshwater and terrestrial organisms have evolved the capacity to synthesize, accumulate and metabolize a variety of UV-absorbing substances called mycosporine-like amino acids (MAAs) as part of an overall strategy to diminish the direct and indirect damaging effects of...

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Detalles Bibliográficos
Autores principales: Carreto, Jose I., Carignan, Mario O.
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083659/
https://www.ncbi.nlm.nih.gov/pubmed/21556168
http://dx.doi.org/10.3390/md9030387
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author Carreto, Jose I.
Carignan, Mario O.
author_facet Carreto, Jose I.
Carignan, Mario O.
author_sort Carreto, Jose I.
collection PubMed
description Taxonomically diverse marine, freshwater and terrestrial organisms have evolved the capacity to synthesize, accumulate and metabolize a variety of UV-absorbing substances called mycosporine-like amino acids (MAAs) as part of an overall strategy to diminish the direct and indirect damaging effects of environmental ultraviolet radiation (UVR). Whereas the enzymatic machinery to synthesize MAAs was probably inherited from cyanobacteria ancestors via the endosymbionts hypothesis, metazoans lack this biochemical pathway, but can acquire and metabolize these compounds by trophic transference, symbiotic or bacterial association. In this review we describe the structure and physicochemical properties of MAAs, including the recently discovered compounds and the modern methods used for their isolation and identification, updating previous reviews. On this basis, we review the metabolism and distribution of this unique class of metabolites among marine organism.
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spelling pubmed-30836592011-05-09 Mycosporine-Like Amino Acids: Relevant Secondary Metabolites. Chemical and Ecological Aspects Carreto, Jose I. Carignan, Mario O. Mar Drugs Review Taxonomically diverse marine, freshwater and terrestrial organisms have evolved the capacity to synthesize, accumulate and metabolize a variety of UV-absorbing substances called mycosporine-like amino acids (MAAs) as part of an overall strategy to diminish the direct and indirect damaging effects of environmental ultraviolet radiation (UVR). Whereas the enzymatic machinery to synthesize MAAs was probably inherited from cyanobacteria ancestors via the endosymbionts hypothesis, metazoans lack this biochemical pathway, but can acquire and metabolize these compounds by trophic transference, symbiotic or bacterial association. In this review we describe the structure and physicochemical properties of MAAs, including the recently discovered compounds and the modern methods used for their isolation and identification, updating previous reviews. On this basis, we review the metabolism and distribution of this unique class of metabolites among marine organism. Molecular Diversity Preservation International 2011-03-21 /pmc/articles/PMC3083659/ /pubmed/21556168 http://dx.doi.org/10.3390/md9030387 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Carreto, Jose I.
Carignan, Mario O.
Mycosporine-Like Amino Acids: Relevant Secondary Metabolites. Chemical and Ecological Aspects
title Mycosporine-Like Amino Acids: Relevant Secondary Metabolites. Chemical and Ecological Aspects
title_full Mycosporine-Like Amino Acids: Relevant Secondary Metabolites. Chemical and Ecological Aspects
title_fullStr Mycosporine-Like Amino Acids: Relevant Secondary Metabolites. Chemical and Ecological Aspects
title_full_unstemmed Mycosporine-Like Amino Acids: Relevant Secondary Metabolites. Chemical and Ecological Aspects
title_short Mycosporine-Like Amino Acids: Relevant Secondary Metabolites. Chemical and Ecological Aspects
title_sort mycosporine-like amino acids: relevant secondary metabolites. chemical and ecological aspects
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083659/
https://www.ncbi.nlm.nih.gov/pubmed/21556168
http://dx.doi.org/10.3390/md9030387
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