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Lipid Rafts and Redox Regulation of Cellular Signaling in Cholesterol Induced Atherosclerosis
Redox mediated signaling mechanisms play crucial roles in the pathogenesis of several cardiovascular diseases. Atherosclerosis is one of the most important disorders induced mainly by hypercholesterolemia. Oxidation products and related signaling mechanisms are found within the characteristic biomar...
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Formato: | Texto |
Lenguaje: | English |
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Bentham Science Publishers Ltd
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083812/ https://www.ncbi.nlm.nih.gov/pubmed/22043207 http://dx.doi.org/10.2174/157340310793566181 |
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author | Catalgol, Betul Kartal Ozer, Nesrin |
author_facet | Catalgol, Betul Kartal Ozer, Nesrin |
author_sort | Catalgol, Betul |
collection | PubMed |
description | Redox mediated signaling mechanisms play crucial roles in the pathogenesis of several cardiovascular diseases. Atherosclerosis is one of the most important disorders induced mainly by hypercholesterolemia. Oxidation products and related signaling mechanisms are found within the characteristic biomarkers of atherosclerosis. Several studies have shown that redox signaling via lipid rafts play a significant role in the regulation of pathogenesis of many diseases including atherosclerosis. This review attempts to summarize redox signaling and lipid rafts in hypercholesterolemia induced atherosclerosis. |
format | Text |
id | pubmed-3083812 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Bentham Science Publishers Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-30838122011-11-01 Lipid Rafts and Redox Regulation of Cellular Signaling in Cholesterol Induced Atherosclerosis Catalgol, Betul Kartal Ozer, Nesrin Curr Cardiol Rev Article Redox mediated signaling mechanisms play crucial roles in the pathogenesis of several cardiovascular diseases. Atherosclerosis is one of the most important disorders induced mainly by hypercholesterolemia. Oxidation products and related signaling mechanisms are found within the characteristic biomarkers of atherosclerosis. Several studies have shown that redox signaling via lipid rafts play a significant role in the regulation of pathogenesis of many diseases including atherosclerosis. This review attempts to summarize redox signaling and lipid rafts in hypercholesterolemia induced atherosclerosis. Bentham Science Publishers Ltd 2010-11 /pmc/articles/PMC3083812/ /pubmed/22043207 http://dx.doi.org/10.2174/157340310793566181 Text en © 2010 Bentham Science Publishers Ltd. http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Article Catalgol, Betul Kartal Ozer, Nesrin Lipid Rafts and Redox Regulation of Cellular Signaling in Cholesterol Induced Atherosclerosis |
title | Lipid Rafts and Redox Regulation of Cellular Signaling in Cholesterol Induced Atherosclerosis |
title_full | Lipid Rafts and Redox Regulation of Cellular Signaling in Cholesterol Induced Atherosclerosis |
title_fullStr | Lipid Rafts and Redox Regulation of Cellular Signaling in Cholesterol Induced Atherosclerosis |
title_full_unstemmed | Lipid Rafts and Redox Regulation of Cellular Signaling in Cholesterol Induced Atherosclerosis |
title_short | Lipid Rafts and Redox Regulation of Cellular Signaling in Cholesterol Induced Atherosclerosis |
title_sort | lipid rafts and redox regulation of cellular signaling in cholesterol induced atherosclerosis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083812/ https://www.ncbi.nlm.nih.gov/pubmed/22043207 http://dx.doi.org/10.2174/157340310793566181 |
work_keys_str_mv | AT catalgolbetul lipidraftsandredoxregulationofcellularsignalingincholesterolinducedatherosclerosis AT kartalozernesrin lipidraftsandredoxregulationofcellularsignalingincholesterolinducedatherosclerosis |