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Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study: Common Genetic Variants in GCK and TCF7L2 Are Associated With Fasting and Postchallenge Glucose Levels in Pregnancy and With the New Consensus Definition of Gestational Diabetes Mellitus From the International Association of Diabetes and Pregnancy Study Groups
OBJECTIVE: Common genetic variants in GCK and TCF7L2 are associated with higher fasting glucose and type 2 diabetes in nonpregnant populations. However, their associations with glucose levels from oral glucose tolerance tests (OGTTs) in pregnancy have not been assessed in a large sample. We hypothes...
Autores principales: | Freathy, Rachel M., Hayes, M. Geoffrey, Urbanek, Margrit, Lowe, Lynn P., Lee, Hoon, Ackerman, Christine, Frayling, Timothy M., Cox, Nancy J., Dunger, David B., Dyer, Alan R., Hattersley, Andrew T., Metzger, Boyd E., Lowe, William L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083839/ https://www.ncbi.nlm.nih.gov/pubmed/20682688 http://dx.doi.org/10.2337/db10-0177 |
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