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Radiation damage in single-particle cryo-electron microscopy: effects of dose and dose rate
Radiation damage is an important resolution limiting factor both in macromolecular X-ray crystallography and cryo-electron microscopy. Systematic studies in macromolecular X-ray crystallography greatly benefited from the use of dose, expressed as energy deposited per mass unit, which is derived from...
Autores principales: | Karuppasamy, Manikandan, Karimi Nejadasl, Fatemeh, Vulovic, Milos, Koster, Abraham J., Ravelli, Raimond B. G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083915/ https://www.ncbi.nlm.nih.gov/pubmed/21525648 http://dx.doi.org/10.1107/S090904951100820X |
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