PTG Depletion Removes Lafora Bodies and Rescues the Fatal Epilepsy of Lafora Disease

Lafora disease is the most common teenage-onset neurodegenerative disease, the main teenage-onset form of progressive myoclonus epilepsy (PME), and one of the severest epilepsies. Pathologically, a starch-like compound, polyglucosan, accumulates in neuronal cell bodies and overtakes neuronal small p...

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Detalles Bibliográficos
Autores principales: Turnbull, Julie, DePaoli-Roach, Anna A., Zhao, Xiaochu, Cortez, Miguel A., Pencea, Nela, Tiberia, Erica, Piliguian, Mark, Roach, Peter J., Wang, Peixiang, Ackerley, Cameron A., Minassian, Berge A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084203/
https://www.ncbi.nlm.nih.gov/pubmed/21552327
http://dx.doi.org/10.1371/journal.pgen.1002037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084203/
https://www.ncbi.nlm.nih.gov/pubmed/21552327
http://dx.doi.org/10.1371/journal.pgen.1002037

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