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Does Positive Selection Drive Transcription Factor Binding Site Turnover? A Test with Drosophila Cis-Regulatory Modules
Transcription factor binding site(s) (TFBS) gain and loss (i.e., turnover) is a well-documented feature of cis-regulatory module (CRM) evolution, yet little attention has been paid to the evolutionary force(s) driving this turnover process. The predominant view, motivated by its widespread occurrenc...
Autores principales: | He, Bin Z., Holloway, Alisha K., Maerkl, Sebastian J., Kreitman, Martin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084208/ https://www.ncbi.nlm.nih.gov/pubmed/21572512 http://dx.doi.org/10.1371/journal.pgen.1002053 |
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