The Complete Spectrum of Yeast Chromosome Instability Genes Identifies Candidate CIN Cancer Genes and Functional Roles for ASTRA Complex Components

Chromosome instability (CIN) is observed in most solid tumors and is linked to somatic mutations in genome integrity maintenance genes. The spectrum of mutations that cause CIN is only partly known and it is not possible to predict a priori all pathways whose disruption might lead to CIN. To address...

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Detalles Bibliográficos
Autores principales: Stirling, Peter C., Bloom, Michelle S., Solanki-Patil, Tejomayee, Smith, Stephanie, Sipahimalani, Payal, Li, Zhijian, Kofoed, Megan, Ben-Aroya, Shay, Myung, Kyungjae, Hieter, Philip
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084213/
https://www.ncbi.nlm.nih.gov/pubmed/21552543
http://dx.doi.org/10.1371/journal.pgen.1002057

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