A complement receptor C5a antagonist regulates epithelial to mesenchymal transition and crystallin expression after lens cataract surgery in mice

PURPOSE: To evaluate the effects of complement employing a mouse model for secondary cataract. METHODS: The role of complement receptor C5a (CD88) was evaluated after cataract surgery in mice. An antagonist specific to C5a receptor was administered intraperitoneally to mice. Epithelial to mesenchyma...

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Detalles Bibliográficos
Autores principales: Suetsugu-Maki, Rinako, Maki, Nobuyasu, Fox, Timothy P., Nakamura, Kenta, Cowper.Solari, Richard, Tomlinson, Craig R., Qu, Hongchang, Lambris, John D., Tsonis, Panagiotis A.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084220/
https://www.ncbi.nlm.nih.gov/pubmed/21541266

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