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Variation in the FFAR1 Gene Modifies BMI, Body Composition and Beta-Cell Function in Overweight Subjects: An Exploratory Analysis
BACKGROUND: FFAR1 receptor is a long chain fatty acid G-protein coupled receptor which is expressed widely, but found in high density in the pancreas and central nervous system. It has been suggested that FFAR1 may play a role in insulin sensitivity, lipotoxicity and is associated with type 2 diabet...
Autores principales: | Walker, Celia G., Goff, Louise, Bluck, Les J., Griffin, Bruce A., Jebb, Susan A., Lovegrove, Julie A., Sanders, Thomas A. B., Frost, Gary S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084254/ https://www.ncbi.nlm.nih.gov/pubmed/21552566 http://dx.doi.org/10.1371/journal.pone.0019146 |
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