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Acoustic Trauma Increases Cochlear and Hair Cell Uptake of Gentamicin
BACKGROUND: Exposure to intense sound or high doses of aminoglycoside antibiotics can increase hearing thresholds, induce cochlear dysfunction, disrupt hair cell morphology and promote hair cell death, leading to permanent hearing loss. When the two insults are combined, synergistic ototoxicity occu...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084257/ https://www.ncbi.nlm.nih.gov/pubmed/21552569 http://dx.doi.org/10.1371/journal.pone.0019130 |