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Alternative Splicing of the Cardiac Sodium Channel Creates Multiple Variants of Mutant T1620K Channels
Alternative splicing creates several Na(v)1.5 transcripts in the mammalian myocardium and in various other tissues including brain, dorsal root ganglia, breast cancer cells as well as neuronal stem cell lines. In total nine Na(v)1.5 splice variants have been discovered. Four of them, namely Na(v)1.5...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084281/ https://www.ncbi.nlm.nih.gov/pubmed/21552533 http://dx.doi.org/10.1371/journal.pone.0019188 |