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Multivariate models to detect genomic signatures for a class of drugs: application to thiopurines pharmacogenomics
Often, analysis for pharmacogenomic studies involving multiple drugs from the same class is completed by analyzing each drug individually for association with genomic variation. However, by completing the analysis of each drug individually, we may be losing valuable information. When studying multip...
Autores principales: | Fridley, B L, Jenkins, G D, Batzler, A, Wang, L, Ji, Y, Li, F, Weinshilboum, R M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084322/ https://www.ncbi.nlm.nih.gov/pubmed/21060324 http://dx.doi.org/10.1038/tpj.2010.83 |
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