Cargando…

The vacuolar-ATPase (V-ATPase) modulates matrix metalloproteinase (MMP) isoforms in human pancreatic cancer

The vacuolar-ATPase (v-ATPase) is a proton transporter found on many intra-cellular organelles and the plasma membrane (PM). The v-ATPase on PMs of cancer cells may contribute to their invasive properties in vitro. Its relevance to human cancer tissues remains unclear. We investigated whether the ex...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chung, Chuhan, Mader, Christopher C, Schmitz, John, Atladottir, Jorunn, Fitchev, Phillip, Cornwell, Mona, Koleske, Anthony J, Crawford, Susan E, Gorelick, Fred
Formato:	Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084324/ https://www.ncbi.nlm.nih.gov/pubmed/21339745 http://dx.doi.org/10.1038/labinvest.2011.8

Ejemplares similares

Vacuolar ATPase ‘a2’ isoform exhibits distinct cell surface accumulation and modulates matrix metalloproteinase activity in ovarian cancer
por: Kulshrestha, Arpita, et al.
Publicado: (2015)

An isoform of the vacuolar (H(+))-ATPase accessory subunit Ac45
por: Jansen, Eric J. R., et al.
Publicado: (2009)

Role of the vacuolar ATPase in the Alphavirus replication cycle
por: Schuchman, Ryan M., et al.
Publicado: (2018)

Advances in targeting the vacuolar proton-translocating ATPase (V-ATPase) for anti-fungal therapy
por: Hayek, Summer R., et al.
Publicado: (2014)

Flexibility within the Rotor and Stators of the Vacuolar H(+)-ATPase
por: Song, Chun Feng, et al.
Publicado: (2013)

Rotating with the brakes on and other unresolved features of the vacuolar ATPase
por: Rawson, Shaun, et al.
Publicado: (2016)

The curious case of vacuolar ATPase: regulation of signaling pathways
por: Pamarthy, Sahithi, et al.
Publicado: (2018)

The a subunit isoforms of vacuolar-type proton ATPase exhibit differential distribution in mouse perigastrulation embryos
por: Sun-Wada, Ge-Hong, et al.
Publicado: (2022)

Extracellular and Luminal pH Regulation by Vacuolar H(+)-ATPase Isoform Expression and Targeting to the Plasma Membrane and Endosomes
por: Smith, Gina A., et al.
Publicado: (2016)

Breast cancer associated a2 isoform vacuolar ATPase immunomodulates neutrophils: potential role in tumor progression
por: Ibrahim, Safaa A., et al.
Publicado: (2015)

The vacuolar H+ ATPase is a novel therapeutic target for glioblastoma
por: Di Cristofori, Andrea, et al.
Publicado: (2015)

Cryo-EM studies of the structure and dynamics of vacuolar-type ATPases
por: Mazhab-Jafari, Mohammad T., et al.
Publicado: (2016)

Vacuolar-type ATPase: A proton pump to lysosomal trafficking
por: FUTAI, Masamitsu, et al.
Publicado: (2019)

RNA Interference of Genes Encoding the Vacuolar-ATPase in Liriomyza trifolii
por: Chang, Ya-Wen, et al.
Publicado: (2021)

Cancer derived peptide of vacuolar ATPase ‘a2’ isoform promotes neutrophil migration by autocrine secretion of IL-8
por: Ibrahim, Safaa A., et al.
Publicado: (2016)

Probing Subunit-Subunit Interactions in the Yeast Vacuolar ATPase by Peptide Arrays
por: Parsons, Lee S., et al.
Publicado: (2012)

Identification of Novel Bisbenzimidazole Derivatives as Anticancer Vacuolar (H(+))-ATPase Inhibitors †
por: Patil, Renukadevi, et al.
Publicado: (2017)

Vacuolar H(+)-ATPase is not restricted to clear cells of the epididymal epithelium in cattle
por: Kim, Sung Woo, et al.
Publicado: (2021)

The role of Plasmodium V-ATPase in vacuolar physiology and antimalarial drug uptake
por: Alder, Arne, et al.
Publicado: (2023)

Reconstitution of Vacuolar-type Rotary H(+)-ATPase/Synthase from Thermus thermophilus
por: Kishikawa, Jun-ichi, et al.
Publicado: (2012)

The Vacuolar-Type H(+)-ATPase in Ovine Rumen Epithelium is Regulated by Metabolic Signals
por: Kuzinski, Judith, et al.
Publicado: (2010)

Inhibition of Host Vacuolar H(+)-ATPase Activity by a Legionella pneumophila Effector
por: Xu, Li, et al.
Publicado: (2010)

The d subunit plays a central role in human vacuolar H(+)-ATPases
por: Smith, Annabel N., et al.
Publicado: (2008)

Retrieval of the Vacuolar H(+)-ATPase from Phagosomes Revealed by Live Cell Imaging
por: Clarke, Margaret, et al.
Publicado: (2010)

A thermo-physical analysis of the proton pump vacuolar-ATPase: the constructal approach
por: Lucia, Umberto, et al.
Publicado: (2014)

Structure of the Vacuolar H(+)-ATPase Rotary Motor Reveals New Mechanistic Insights
por: Rawson, Shaun, et al.
Publicado: (2015)

Vacuolar ATPase as a potential therapeutic target and mediator of treatment resistance in cancer
por: Whitton, Bradleigh, et al.
Publicado: (2018)

Clathrin coat controls synaptic vesicle acidification by blocking vacuolar ATPase activity
por: Farsi, Zohreh, et al.
Publicado: (2018)

Antiviral efficacy of nanoparticulate vacuolar ATPase inhibitors against influenza virus infection
por: Hu, Che-Ming Jack, et al.
Publicado: (2018)

Vacuolar proton-translocating ATPase is required for antifungal resistance and virulence of Candida glabrata
por: Minematsu, Asuka, et al.
Publicado: (2019)

Hyperacidification of Citrus fruits by a vacuolar proton-pumping P-ATPase complex
por: Strazzer, Pamela, et al.
Publicado: (2019)

Cancer with low cathepsin D levels is susceptible to vacuolar (H(+))‐ATPase inhibition
por: Kitazawa, Satoshi, et al.
Publicado: (2017)

Pharmacologic inhibition of vacuolar H+ ATPase reduces physiologic and oncogenic Notch signaling
por: Kobia, Francis, et al.
Publicado: (2013)

Vacuolar ATPase depletion contributes to dysregulation of endocytosis in bloodstream forms of Trypanosoma brucei
por: Xu, Zhi-Shen, et al.
Publicado: (2020)

The emerging roles of vacuolar-type ATPase-dependent Lysosomal acidification in neurodegenerative diseases
por: Song, Qiaoyun, et al.
Publicado: (2020)

Purification of active human vacuolar H(+)-ATPase in native lipid-containing nanodiscs
por: Oot, Rebecca A., et al.
Publicado: (2021)

Acidification of endothelial Weibel-Palade bodies is mediated by the vacuolar-type H(+)-ATPase
por: Terglane, Julian, et al.
Publicado: (2022)

TFEB-vacuolar ATPase signaling regulates lysosomal function and microglial activation in tauopathy
por: Wang, Baiping, et al.
Publicado: (2023)

Acidification of the lysosome-like vacuole and the vacuolar H+-ATPase are deficient in two yeast mutants that fail to sort vacuolar proteins
Publicado: (1989)

Proton pump inhibitors as anti vacuolar-ATPases drugs: a novel anticancer strategy
por: Spugnini, Enrico P, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_k41j5rmt3gqqqvhkt554pth814