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Differential microRNA regulation of HLA-C expression and its association with HIV control

The HLA-C locus is distinct relative to the other classical HLA class I loci in that it has relatively limited polymorphism1, lower expression on the cell surface2,3, and more extensive ligand-receptor interactions with killer cell immunoglobulin-like receptors (KIR)4. A single nucleotide polymorphi...

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Detalles Bibliográficos
Autores principales: Kulkarni, Smita, Savan, Ram, Qi, Ying, Gao, Xiaojiang, Yuki, Yuko, Bass, Sara E., Martin, Maureen P., Hunt, Peter, Deeks, Steven G., Telenti, Amalio, Pereyra, Florencia, Goldstein, David, Wolinsky, Steven, Walker, Bruce, Young, Howard A., Carrington, Mary
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084326/
https://www.ncbi.nlm.nih.gov/pubmed/21499264
http://dx.doi.org/10.1038/nature09914