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Is Ciprofloxacin a Substrate of P-glycoprotein?

INTRODUCTION: Studies using MDCKII and LLC-PK1 cells transfected with MDR1 cDNA indicate that ciprofloxacin is not a substrate of P-glycoprotein. However, our data has shown that transport studies done using different P-gp overexpressing cell lines (MDCKI-MDR1, MDCKII-MDR1 and L-MDR1), could lead to...

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Detalles Bibliográficos
Autores principales:	Park, Miki Susanto, Okochi, Hideaki, Benet, Leslie Z
Formato:	Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Inc 2011
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084506/ https://www.ncbi.nlm.nih.gov/pubmed/21572514 http://dx.doi.org/10.1111/j.1753-5174.2010.00032.x

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