Honokiol Crosses BBB and BCSFB, and Inhibits Brain Tumor Growth in Rat 9L Intracerebral Gliosarcoma Model and Human U251 Xenograft Glioma Model

BACKGROUND: Gliosarcoma is one of the most common malignant brain tumors, and anti-angiogenesis is a promising approach for the treatment of gliosarcoma. However, chemotherapy is obstructed by the physical obstacle formed by the blood-brain barrier (BBB) and blood-cerebrospinal fluid barrier (BCSFB)...

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Detalles Bibliográficos
Autores principales: Wang, Xianhuo, Duan, Xingmei, Yang, Guangli, Zhang, Xiaoyan, Deng, Linyu, Zheng, Hao, Deng, Chongyang, Wen, Jiaolin, Wang, Ning, Peng, Cheng, Zhao, Xia, Wei, Yuquan, Chen, Lijuan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084695/
https://www.ncbi.nlm.nih.gov/pubmed/21559510
http://dx.doi.org/10.1371/journal.pone.0018490

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