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Toll-Like Receptor 9 Is Required for Opioid-Induced Microglia Apoptosis

Opioids have been widely applied in clinics as one of the most potent pain relievers for centuries, but their abuse has deleterious physiological effects beyond addiction. However, the underlying mechanism by which microglia in response to opioids remains largely unknown. Here we show that morphine...

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Detalles Bibliográficos
Autores principales: He, Lei, Li, Hui, Chen, Lin, Miao, Junying, Jiang, Yulin, Zhang, Yi, Xiao, Zuoxiang, Hanley, Gregory, Li, Yi, Zhang, Xiumei, LeSage, Gene, Peng, Ying, Yin, Deling
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084705/
https://www.ncbi.nlm.nih.gov/pubmed/21559519
http://dx.doi.org/10.1371/journal.pone.0018190

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