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cDNA Immunization of Mice with Human Thyroglobulin Generates Both Humoral and T Cell Responses: A Novel Model of Thyroid Autoimmunity

Thyroglobulin (Tg) represents one of the largest known self-antigens involved in autoimmunity. Numerous studies have implicated it in triggering and perpetuating the autoimmune response in autoimmune thyroid diseases (AITD). Indeed, traditional models of autoimmune thyroid disease, experimental auto...

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Detalles Bibliográficos
Autores principales: Jacobson, Eric M., Concepcion, Erlinda, Ho, Kenneth, Kopp, Peter, Vono Toniolo, Jussara, Tomer, Yaron
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084781/
https://www.ncbi.nlm.nih.gov/pubmed/21559421
http://dx.doi.org/10.1371/journal.pone.0019200

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