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cDNA Immunization of Mice with Human Thyroglobulin Generates Both Humoral and T Cell Responses: A Novel Model of Thyroid Autoimmunity
Thyroglobulin (Tg) represents one of the largest known self-antigens involved in autoimmunity. Numerous studies have implicated it in triggering and perpetuating the autoimmune response in autoimmune thyroid diseases (AITD). Indeed, traditional models of autoimmune thyroid disease, experimental auto...
Autores principales: | Jacobson, Eric M., Concepcion, Erlinda, Ho, Kenneth, Kopp, Peter, Vono Toniolo, Jussara, Tomer, Yaron |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084781/ https://www.ncbi.nlm.nih.gov/pubmed/21559421 http://dx.doi.org/10.1371/journal.pone.0019200 |
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