Hypoxia-Induced Down-Regulation of Neprilysin by Histone Modification in Mouse Primary Cortical and Hippocampal Neurons

Amyloid β-peptide (Aβ) accumulation leads to neurodegeneration and Alzheimer's disease (AD). Aβ metabolism is a dynamic process in the Aβ production and clearance that requires neprilysin (NEP) and other enzymes to degrade Aβ. It has been reported that NEP expression is significantly decreased...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Zheng, Yang, Dehua, Zhang, Xiaojie, Li, Ting, Li, Jia, Tang, Yu, Le, Weidong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084787/
https://www.ncbi.nlm.nih.gov/pubmed/21559427
http://dx.doi.org/10.1371/journal.pone.0019229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084787/
https://www.ncbi.nlm.nih.gov/pubmed/21559427
http://dx.doi.org/10.1371/journal.pone.0019229

Ejemplares similares