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Decreased Dengue Replication and an Increased Anti-viral Humoral Response with the use of Combined Toll-Like Receptor 3 and 7/8 Agonists in Macaques

BACKGROUND: Pathogenic versus protective outcomes to Dengue virus (DENV) infection are associated with innate immune function. This study aimed to determine the role of increased TLR3- and TLR7/8-mediated innate signaling after Dengue infection of rhesus macaques in vivo to evaluate its impact on di...

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Detalles Bibliográficos
Autores principales:	Sariol, Carlos A., Martínez, Melween I., Rivera, Francheska, Rodríguez, Idia Vanessa, Pantoja, Petraleigh, Abel, Kristina, Arana, Teresa, Giavedoni, Luis, Hodara, Vida, White, Laura J., Angleró, Yesseinia I., Montaner, Luis J., Kraiselburd, Edmundo N.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084804/ https://www.ncbi.nlm.nih.gov/pubmed/21559444 http://dx.doi.org/10.1371/journal.pone.0019323

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