Genome-Wide DNA Methylation Analysis Reveals Phytoestrogen Modification of Promoter Methylation Patterns during Embryonic Stem Cell Differentiation

BACKGROUND: Environmental challenges during development affect the fetal epigenome, but the period(s) vulnerable to epigenetic dysregulation is(are) not clear. By employing a soy phytoestrogen, genistein, that is known to alter the epigenetic states of the A(vy) allele during embryogenesis, we have...

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Detalles Bibliográficos
Autores principales: Sato, Noriko, Yamakawa, Naomi, Masuda, Moe, Sudo, Katsuko, Hatada, Izuho, Muramatsu, Masaaki
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084807/
https://www.ncbi.nlm.nih.gov/pubmed/21559447
http://dx.doi.org/10.1371/journal.pone.0019278

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