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Monitoring the Systemic Human Memory B Cell Compartment of Melanoma Patients for Anti-Tumor IgG Antibodies

Melanoma, a potentially lethal skin cancer, is widely thought to be immunogenic in nature. While there has been much focus on T cell-mediated immune responses, limited knowledge exists on the role of mature B cells. We describe an approach, including a cell-based ELISA, to evaluate mature IgG antibo...

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Detalles Bibliográficos
Autores principales: Gilbert, Amy E., Karagiannis, Panagiotis, Dodev, Tihomir, Koers, Alexander, Lacy, Katie, Josephs, Debra H., Takhar, Pooja, Geh, Jenny L. C., Healy, Ciaran, Harries, Mark, Acland, Katharine M., Rudman, Sarah M., Beavil, Rebecca L., Blower, Philip J., Beavil, Andrew J., Gould, Hannah J., Spicer, James, Nestle, Frank O., Karagiannis, Sophia N.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084832/
https://www.ncbi.nlm.nih.gov/pubmed/21559411
http://dx.doi.org/10.1371/journal.pone.0019330