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An ENU-Mutagenesis Screen in the Mouse: Identification of Novel Developmental Gene Functions

BACKGROUND: Mutagenesis screens in the mouse have been proven useful for the identification of novel gene functions and generation of interesting mutant alleles. Here we describe a phenotype-based screen for recessive mutations affecting embryonic development. METHODOLOGY/PRINCIPAL FINDINGS: Mice we...

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Detalles Bibliográficos
Autores principales:	Wansleeben, Carolien, van Gurp, Léon, Feitsma, Harma, Kroon, Carla, Rieter, Ester, Verberne, Marlies, Guryev, Victor, Cuppen, Edwin, Meijlink, Frits
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084836/ https://www.ncbi.nlm.nih.gov/pubmed/21559415 http://dx.doi.org/10.1371/journal.pone.0019357

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