Enantioselective Protein-Sterol Interactions Mediate Regulation of Both Prokaryotic and Eukaryotic Inward Rectifier K(+) Channels by Cholesterol

Cholesterol is the major sterol component of all mammalian cell plasma membranes and plays a critical role in cell function and growth. Previous studies have shown that cholesterol inhibits inward rectifier K(+) (Kir) channels, but have not distinguished whether this is due directly to protein-stero...

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Detalles Bibliográficos
Autores principales: D'Avanzo, Nazzareno, Hyrc, Krzysztof, Enkvetchakul, Decha, Covey, Douglas F., Nichols, Colin G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084843/
https://www.ncbi.nlm.nih.gov/pubmed/21559361
http://dx.doi.org/10.1371/journal.pone.0019393

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