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A Genetic Risk Score Combining Ten Psoriasis Risk Loci Improves Disease Prediction
Psoriasis is a chronic, immune-mediated skin disease affecting 2–3% of Caucasians. Recent genetic association studies have identified multiple psoriasis risk loci; however, most of these loci contribute only modestly to disease risk. In this study, we investigated whether a genetic risk score (GRS)...
Autores principales: | Chen, Haoyan, Poon, Annie, Yeung, Celestine, Helms, Cynthia, Pons, Jennifer, Bowcock, Anne M., Kwok, Pui-Yan, Liao, Wilson |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084857/ https://www.ncbi.nlm.nih.gov/pubmed/21559375 http://dx.doi.org/10.1371/journal.pone.0019454 |
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