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Age-Related Retinopathy in NRF2-Deficient Mice

BACKGROUND: Cumulative oxidative damage is implicated in the pathogenesis of age-related macular degeneration (AMD). Nuclear factor erythroid 2-related factor 2 (NRF2) is a transcription factor that plays key roles in retinal antioxidant and detoxification responses. The purposes of this study were...

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Detalles Bibliográficos
Autores principales:	Zhao, Zhenyang, Chen, Yan, Wang, Jian, Sternberg, Paul, Freeman, Michael L., Grossniklaus, Hans E., Cai, Jiyang
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084871/ https://www.ncbi.nlm.nih.gov/pubmed/21559389 http://dx.doi.org/10.1371/journal.pone.0019456

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