Valosin-Containing Protein Gene Mutations: Cellular Phenotypes Relevant to Neurodegeneration

Previously, we identified valosin-containing protein (VCP) as a mediator of ER stress-induced cell death. Mutations in the VCP gene including R93, R155, and R191 have been described that manifest clinically as hereditary inclusion body myopathy with Paget’s disease of bone and frontotemporal dementi...

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Detalles Bibliográficos
Autores principales: Poksay, Karen S., Madden, David T., Peter, Anna K., Niazi, Kayvan, Banwait, Surita, Crippen, Danielle, Bredesen, Dale E., Rao, Rammohan V.
Formato: Texto
Lenguaje:English
Publicado: Humana Press Inc 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084943/
https://www.ncbi.nlm.nih.gov/pubmed/21249466
http://dx.doi.org/10.1007/s12031-010-9489-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084943/
https://www.ncbi.nlm.nih.gov/pubmed/21249466
http://dx.doi.org/10.1007/s12031-010-9489-8

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