Glial nuclear aggregates of superoxide dismutase-1 are regularly present in patients with amyotrophic lateral sclerosis

The most common cause of amyotrophic lateral sclerosis (ALS) is mutations in superoxide dismutase-1 (SOD1). Since there is evidence for the involvement of non-neuronal cells in ALS, we searched for signs of SOD1 abnormalities focusing on glia. Spinal cords from nine ALS patients carrying SOD1 mutati...

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Detalles Bibliográficos
Autores principales: Forsberg, Karin, Andersen, Peter M., Marklund, Stefan L., Brännström, Thomas
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085063/
https://www.ncbi.nlm.nih.gov/pubmed/21287393
http://dx.doi.org/10.1007/s00401-011-0805-3

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