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A novel desmocollin-2 mutation reveals insights into the molecular link between desmosomes and gap junctions

BACKGROUND: Cellular adhesion mediated by cardiac desmosomes is a prerequisite for proper electric propagation mediated by gap junctions in the myocardium. However, the molecular principles underlying this interdependence are not fully understood. OBJECTIVE: The purpose of this study was to determin...

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Detalles Bibliográficos
Autores principales: Gehmlich, Katja, Lambiase, Pier D., Asimaki, Angeliki, Ciaccio, Edward J., Ehler, Elisabeth, Syrris, Petros, Saffitz, Jeffrey E., McKenna, William J.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085091/
https://www.ncbi.nlm.nih.gov/pubmed/21220045
http://dx.doi.org/10.1016/j.hrthm.2011.01.010

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