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PET imaging of CXCR4 using copper-64 labeled peptide antagonist
Expression of CXCR4 in cancer has been found to correlate with poor prognosis and resistance to chemotherapy. In this study we developed a derivative of the CXCR4 peptide antagonist, T140-2D, that can be labeled easily with the PET isotope copper-64, and thereby enable in vivo visualization of CXCR4...
Autores principales: | Jacobson, Orit, Weiss, Ido D., Szajek, Lawrence P., Niu, Gang, Ma, Ying, Kiesewetter, Dale O., Farber, Joshua M., Chen, Xiaoyuan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085282/ https://www.ncbi.nlm.nih.gov/pubmed/21544263 |
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