ModEnzA: Accurate Identification of Metabolic Enzymes Using Function Specific Profile HMMs with Optimised Discrimination Threshold and Modified Emission Probabilities

Various enzyme identification protocols involving homology transfer by sequence-sequence or profile-sequence comparisons have been devised which utilise Swiss-Prot sequences associated with EC numbers as the training set. A profile HMM constructed for a particular EC number might select sequences wh...

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Detalles Bibliográficos
Autores principales: Desai, Dhwani K., Nandi, Soumyadeep, Srivastava, Prashant K., Lynn, Andrew M.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085309/
https://www.ncbi.nlm.nih.gov/pubmed/21541071
http://dx.doi.org/10.1155/2011/743782

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