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Transcriptional activity of the 5′-flanking region of the thyroid transcription factor-1 gene in human thyroid cell lines

Thyroid transcription factor-1 (TTF-1, NKX2-1) is a homeodomain-containing transcriptional factor that binds to and activates the promoters of thyroid and lung-specific genes, such as thyroglobulin, thyroid peroxidase, and thyroid stimulating hormone receptor. TTF-1 is known to play a key role in th...

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Detalles Bibliográficos
Autores principales: Yamada, Hiroya, Takano, Toru, Matsuzuka, Fumio, Watanabe, Mikio, Miyauchi, Akira, Iwatani, Yoshinori
Formato: Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085375/
https://www.ncbi.nlm.nih.gov/pubmed/21637535
http://dx.doi.org/10.1590/S1415-47572010005000109