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Transcriptional activity of the 5′-flanking region of the thyroid transcription factor-1 gene in human thyroid cell lines
Thyroid transcription factor-1 (TTF-1, NKX2-1) is a homeodomain-containing transcriptional factor that binds to and activates the promoters of thyroid and lung-specific genes, such as thyroglobulin, thyroid peroxidase, and thyroid stimulating hormone receptor. TTF-1 is known to play a key role in th...
Autores principales: | Yamada, Hiroya, Takano, Toru, Matsuzuka, Fumio, Watanabe, Mikio, Miyauchi, Akira, Iwatani, Yoshinori |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Genética
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085375/ https://www.ncbi.nlm.nih.gov/pubmed/21637535 http://dx.doi.org/10.1590/S1415-47572010005000109 |
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