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Adeno-associated virus-mediated gene delivery into the scala media of the normal and deafened adult mouse ear
Murine models are ideal for studying cochlear gene transfer as many hearing loss-related mutations have been discovered and mapped within the mouse genome. However, due to its small size and delicate nature, the membranous labyrinth of the mouse is a challenging target for delivery of viral vectors....
Autores principales: | Kilpatrick, Lauren A., Li, Qian, Yang, John, Goddard, John C, Fekete, Donna M., Lang, Hainan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085601/ https://www.ncbi.nlm.nih.gov/pubmed/21209625 http://dx.doi.org/10.1038/gt.2010.175 |
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