Different host cell proteases activate the SARS-coronavirus spike-protein for cell–cell and virus–cell fusion

Severe acute respiratory syndrome coronavirus (SARS-CoV) poses a considerable threat to human health. Activation of the viral spike (S)-protein by host cell proteases is essential for viral infectivity. However, the cleavage sites in SARS-S and the protease(s) activating SARS-S are incompletely defi...

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Detalles Bibliográficos
Autores principales: Simmons, Graham, Bertram, Stephanie, Glowacka, Ilona, Steffen, Imke, Chaipan, Chawaree, Agudelo, Juliet, Lu, Kai, Rennekamp, Andrew J., Hofmann, Heike, Bates, Paul, Pöhlmann, Stefan
Formato: Texto
Lenguaje:English
Publicado: Elsevier Inc. 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086175/
https://www.ncbi.nlm.nih.gov/pubmed/21435673
http://dx.doi.org/10.1016/j.virol.2011.02.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086175/
https://www.ncbi.nlm.nih.gov/pubmed/21435673
http://dx.doi.org/10.1016/j.virol.2011.02.020

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