Cargando…

Different host cell proteases activate the SARS-coronavirus spike-protein for cell–cell and virus–cell fusion

Severe acute respiratory syndrome coronavirus (SARS-CoV) poses a considerable threat to human health. Activation of the viral spike (S)-protein by host cell proteases is essential for viral infectivity. However, the cleavage sites in SARS-S and the protease(s) activating SARS-S are incompletely defi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Simmons, Graham, Bertram, Stephanie, Glowacka, Ilona, Steffen, Imke, Chaipan, Chawaree, Agudelo, Juliet, Lu, Kai, Rennekamp, Andrew J., Hofmann, Heike, Bates, Paul, Pöhlmann, Stefan
Formato:	Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086175/ https://www.ncbi.nlm.nih.gov/pubmed/21435673 http://dx.doi.org/10.1016/j.virol.2011.02.020

Ejemplares similares

Incorporation of podoplanin into HIV released from HEK-293T cells, but not PBMC, is required for efficient binding to the attachment factor CLEC-2
por: Chaipan, Chawaree, et al.
Publicado: (2010)

Proteolysis of Sars-Associated Coronavirus Spike Glycoprotein
por: Simmons, Graham, et al.
Publicado: (2006)

Impact of polymorphisms in the DC-SIGNR neck domain on the interaction with pathogens
por: Gramberg, Thomas, et al.
Publicado: (2006)

Priming Time: How Cellular Proteases Arm Coronavirus Spike Proteins
por: Hoffmann, Markus, et al.
Publicado: (2018)

Cathepsins B and L activate Ebola but not Marburg virus glycoproteins for efficient entry into cell lines and macrophages independent of TMPRSS2 expression
por: Gnirß, Kerstin, et al.
Publicado: (2012)

Cellular Entry of the SARS Coronavirus: Implications for Transmission, Pathogenicity and Antiviral Strategies
por: Glowacka, Ilona, et al.
Publicado: (2009)

Protease inhibitors targeting coronavirus and filovirus entry
por: Zhou, Yanchen, et al.
Publicado: (2015)

Different residues in the SARS-CoV spike protein determine cleavage and activation by the host cell protease TMPRSS2
por: Reinke, Lennart Michel, et al.
Publicado: (2017)

High Throughput Screening of Protease Inhibitor Libraries Using a Novel Dual Pseudotype-Based Assay for SARS-CoV Entry
por: Zhou, Yanchen, et al.
Publicado: (2009)

Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients
por: Delviks-Frankenberry, Krista A., et al.
Publicado: (2011)

Mutational Analysis of the Murine Coronavirus Spike Protein: Effect on Cell-to-Cell Fusion
por: BOS, EVELYNE C.W., et al.
Publicado: (1995)

Lectin-like interactions in virus–cell recognition: Human immunodeficiency virus and C-type lectin interactions
por: Steffen, Imke, et al.
Publicado: (2010)

Proteolytic activation of the SARS-coronavirus spike protein: Cutting enzymes at the cutting edge of antiviral research
por: Simmons, Graham, et al.
Publicado: (2013)

Host Cell Factors in Filovirus Entry: Novel Players, New Insights
por: Hofmann-Winkler, Heike, et al.
Publicado: (2012)

Roles in Cell-to-Cell Fusion of Two Conserved Hydrophobic Regions in the Murine Coronavirus Spike Protein()
por: Luo, Zongli, et al.
Publicado: (1998)

Palmitoylation of the cysteine-rich endodomain of the SARS–coronavirus spike glycoprotein is important for spike-mediated cell fusion
por: Petit, Chad M., et al.
Publicado: (2007)

Interaction Between the Spike Protein of Human Coronavirus NL63 and its Cellular Receptor ACE2
por: Pöhlmann, Stefan, et al.
Publicado: (2006)

Cellular entry of the SARS coronavirus
por: Hofmann, Heike, et al.
Publicado: (2004)

Genetic analysis of the SARS-coronavirus spike glycoprotein functional domains involved in cell-surface expression and cell-to-cell fusion
por: Petit, Chad M., et al.
Publicado: (2005)

LSECtin interacts with filovirus glycoproteins and the spike protein of SARS coronavirus
por: Gramberg, Thomas, et al.
Publicado: (2005)

The S2 subunit of the spike glycoprotein of bovine coronavirus mediates membrane fusion in insect cells
por: Yoo, Dongwan, et al.
Publicado: (1991)

Furin cleavage of the SARS coronavirus spike glycoprotein enhances cell–cell fusion but does not affect virion entry
por: Follis, Kathryn E., et al.
Publicado: (2006)

Furin cleavage is required for swine acute diarrhea syndrome coronavirus spike protein-mediated cell – cell fusion
por: Kim, Jinman, et al.
Publicado: (2022)

Acquisition of Cell–Cell Fusion Activity by Amino Acid Substitutions in Spike Protein Determines the Infectivity of a Coronavirus in Cultured Cells
por: Yamada, Yoshiyuki, et al.
Publicado: (2009)

The Ebola Virus Glycoprotein and HIV-1 Vpu Employ Different Strategies to Counteract the Antiviral Factor Tetherin
por: Kühl, Annika, et al.
Publicado: (2011)

Comparative Analysis of Host Cell Entry of Ebola Virus From Sierra Leone, 2014, and Zaire, 1976
por: Hofmann-Winkler, Heike, et al.
Publicado: (2015)

TMPRSS2 Isoform 1 Activates Respiratory Viruses and Is Expressed in Viral Target Cells
por: Zmora, Pawel, et al.
Publicado: (2015)

Cleavage of the SARS Coronavirus Spike Glycoprotein by Airway Proteases Enhances Virus Entry into Human Bronchial Epithelial Cells In Vitro
por: Kam, Yiu-Wing, et al.
Publicado: (2009)

Pre-fusion structure of a human coronavirus spike protein
por: Kirchdoerfer, Robert N., et al.
Publicado: (2016)

Spike proteins of novel MERS-coronavirus isolates from North- and West-African dromedary camels mediate robust viral entry into human target cells
por: Kleine-Weber, Hannah, et al.
Publicado: (2019)

ADAM10 and ADAM17 promote SARS‐CoV‐2 cell entry and spike protein‐mediated lung cell fusion
por: Jocher, Georg, et al.
Publicado: (2022)

TCR Fingerprinting and Off-Target Peptide Identification
por: Karapetyan, Armen R., et al.
Publicado: (2019)

Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion
por: Papa, Guido, et al.
Publicado: (2021)

Lung cell entry, cell–cell fusion capacity, and neutralisation sensitivity of omicron sublineage BA.2.75
por: Arora, Prerna, et al.
Publicado: (2022)

A Role for a Protease in Morphogenic Responses during Yeast Cell Fusion
por: Elia, Lisa, et al.
Publicado: (1998)

The SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airways
por: Laporte, Manon, et al.
Publicado: (2021)

Primate Simplexviruses Differ in Tropism for Macaque Cells
por: Hofmann-Winkler, Heike, et al.
Publicado: (2022)

New Consensus pattern in Spike CoV-2: potential implications in coagulation process and cell–cell fusion
por: Buonvino, Silvia, et al.
Publicado: (2020)

A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells
por: Hoffmann, Markus, et al.
Publicado: (2020)

Spike Protein Fusion Peptide and Feline Coronavirus Virulence
por: Chang, Hui-Wen, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_6rid85egb1ofks3ebnhtqm47ss