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A Model for NAD(P)H:Quinoneoxidoreductase 1 (NQO1) Targeted Individualized Cancer Chemotherapy

NQO1 (NAD(P)H:quinoneoxidoreductase 1) is a reductive enzyme that is an important activator of bioreductive antitumor agents. NQO1 activity varies in individual tumors but is generally higher in tumor cells than in normal cells. NQO1 has been used as a target for tumor specific drug development. We...

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Detalles Bibliográficos
Autores principales:	Begleiter, Asher, El-Gabalawy, Nadia, Lange, Laurie, Leith, Marsha K., Guziec, Lynn J., Guziec, Frank S.
Formato:	Texto
Lenguaje:	English
Publicado:	Libertas Academica 2009
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086316/ https://www.ncbi.nlm.nih.gov/pubmed/21904446

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