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Mapping the Conformational Dynamics and Pathways of Spontaneous Steric Zipper Peptide Oligomerization
The process of protein misfolding and self-assembly into various, polymorphic aggregates is associated with a number of important neurodegenerative diseases. Only recently, crystal structures of several short peptides have provided detailed structural insights into [Image: see text]-sheet rich aggre...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086902/ https://www.ncbi.nlm.nih.gov/pubmed/21559277 http://dx.doi.org/10.1371/journal.pone.0019129 |