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Novel CCL21-Vault Nanocapsule Intratumoral Delivery Inhibits Lung Cancer Growth
BACKGROUND: Based on our preclinical findings, we are assessing the efficacy of intratumoral injection of dendritic cells (DC) transduced with an adenoviral vector expressing the secondary lymphoid chemokine (CCL21) gene (Ad-CCL21-DC) in a phase I trial in advanced non-small cell lung cancer (NSCLC)...
Autores principales: | Kar, Upendra K., Srivastava, Minu K., Andersson, Åsa, Baratelli, Felicita, Huang, Min, Kickhoefer, Valerie A., Dubinett, Steven M., Rome, Leonard H., Sharma, Sherven |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086906/ https://www.ncbi.nlm.nih.gov/pubmed/21559281 http://dx.doi.org/10.1371/journal.pone.0018758 |
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