Membrane Incorporation, Channel Formation, and Disruption of Calcium Homeostasis by Alzheimer's β-Amyloid Protein

Oligomerization, conformational changes, and the consequent neurodegeneration of Alzheimer's β-amyloid protein (AβP) play crucial roles in the pathogenesis of Alzheimer's disease (AD). Mounting evidence suggests that oligomeric AβPs cause the disruption of calcium homeostasis, eventually l...

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Detalles Bibliográficos
Autores principales: Kawahara, Masahiro, Ohtsuka, Isao, Yokoyama, Shoko, Kato-Negishi, Midori, Sadakane, Yutaka
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087492/
https://www.ncbi.nlm.nih.gov/pubmed/21547225
http://dx.doi.org/10.4061/2011/304583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087492/
https://www.ncbi.nlm.nih.gov/pubmed/21547225
http://dx.doi.org/10.4061/2011/304583

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