Structure of HLA-A*0301 in complex with a peptide of proteolipid protein: insights into the role of HLA-­A alleles in susceptibility to multiple sclerosis

The structure of the human major histocompatability (MHC) class I molecule HLA-A*0301 (HLA-A3) in complex with a nonameric peptide (KLIETYFSK) has been determined by X-­ray crystallography to 2.7 Å resolution. HLA-A3 is a predisposing allele for multiple sclerosis (MS), an auto­immune disease of the...

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Detalles Bibliográficos
Autores principales: McMahon, Róisín M., Friis, Lone, Siebold, Christian, Friese, Manuel A., Fugger, Lars, Jones, E. Yvonne
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087623/
https://www.ncbi.nlm.nih.gov/pubmed/21543847
http://dx.doi.org/10.1107/S0907444911007888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087623/
https://www.ncbi.nlm.nih.gov/pubmed/21543847
http://dx.doi.org/10.1107/S0907444911007888

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