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Identifying Human Disease Genes through Cross-Species Gene Mapping of Evolutionary Conserved Processes

BACKGROUND: Understanding complex networks that modulate development in humans is hampered by genetic and phenotypic heterogeneity within and between populations. Here we present a method that exploits natural variation in highly diverse mouse genetic reference panels in which genetic and environmen...

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Detalles Bibliográficos
Autores principales: Poot, Martin, Badea, Alexandra, Williams, Robert W., Kas, Martien J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087714/
https://www.ncbi.nlm.nih.gov/pubmed/21572526
http://dx.doi.org/10.1371/journal.pone.0018612