High Abundance Proteins Depletion vs Low Abundance Proteins Enrichment: Comparison of Methods to Reduce the Plasma Proteome Complexity

BACKGROUND: To date, the complexity of the plasma proteome exceeds the analytical capacity of conventional approaches to isolate lower abundance proteins that may prove to be informative biomarkers. Only complex multistep separation strategies have been able to detect a substantial number of low abu...

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Detalles Bibliográficos
Autores principales: Millioni, Renato, Tolin, Serena, Puricelli, Lucia, Sbrignadello, Stefano, Fadini, Gian Paolo, Tessari, Paolo, Arrigoni, Giorgio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087803/
https://www.ncbi.nlm.nih.gov/pubmed/21573190
http://dx.doi.org/10.1371/journal.pone.0019603

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